"Ugly Duckling's Love Revolution" centers on Kawahara Chisato, a high school girl who struggles with her self-image due to being overweight. Her life takes a turn when she encounters four attractive and popular boys—Tachibana Kyouya, Nanami Ryouichi, Fujimoto Shou, and Kurosawa Yuu—who are part of the school's student council. After an incident where Chisato helps one of them, the group decides to assist her in transforming her lifestyle, aiming to boost her confidence and improve her health.

The narrative explores Chisato's journey as she works to lose weight, guided by the boys' support and encouragement. Each of the four boys has a distinct personality and approach to helping her, creating a dynamic interplay of relationships. Tachibana Kyouya, the serious and disciplined student council president, often acts as the driving force behind the group's efforts. Nanami Ryouichi, the cheerful and athletic vice president, provides motivation through his energetic demeanor. Fujimoto Shou, the quiet and observant treasurer, offers subtle but meaningful support, while Kurosawa Yuu, the playful and flirtatious secretary, adds a lighthearted touch to their interactions.

As Chisato progresses in her transformation, the story delves into her growing self-awareness and the complexities of her relationships with the boys. Romantic tensions emerge, with each boy developing feelings for her in their own way, leading to moments of rivalry and introspection. The series balances themes of personal growth, friendship, and romance, portraying Chisato's evolution not just physically but also emotionally as she learns to value herself beyond societal expectations.

The manga maintains a light, comedic tone while addressing deeper issues of self-esteem and body image. It avoids overly dramatic or unrealistic portrayals of weight loss, instead focusing on Chisato's gradual progress and the supportive bonds she forms with the boys. Through its blend of humor, romance, and character development, "Ugly Duckling's Love Revolution" offers a heartfelt exploration of self-improvement and the impact of genuine connections.