"Isshodayo. - Kurumaisu no Kare to no Kekkon · Shussan Monogatari" is a manga that explores the challenges and triumphs of love, marriage, and parenthood through the lens of a relationship between a wheelchair user and his partner. The protagonist, a young woman named Ayaka, meets and falls in love with Shota, a man who uses a wheelchair due to a spinal cord injury. Their relationship evolves from friendship to romance, culminating in marriage. The narrative delves into the societal and personal obstacles they face, including societal prejudices, accessibility issues, and the complexities of intimacy and family planning.

As the story progresses, Ayaka and Shota navigate the realities of married life, including their decision to start a family. The manga provides a detailed portrayal of their journey through pregnancy, childbirth, and parenting, highlighting the unique challenges they encounter due to Shota's disability. The couple's determination and mutual support are central themes, as they work together to overcome barriers and build a fulfilling life.

The characters are depicted with depth and realism, with Ayaka's resilience and Shota's optimism serving as driving forces in their relationship. The manga also introduces supporting characters, such as family members and friends, who provide additional perspectives on disability, relationships, and societal attitudes. The story balances emotional moments with practical insights, offering a nuanced portrayal of disability and family life. Through its focus on love, perseverance, and the everyday realities of living with a disability, the manga provides a heartfelt and informative narrative.