"Mobile Suit Gundam Wing: Blind Target" is a manga sequel to the "Mobile Suit Gundam Wing" anime series, set in the After Colony timeline. The story takes place after the events of the Eve Wars, focusing on the Gundam pilots as they navigate a fragile peace and new threats. The narrative centers on a conspiracy involving the Barton Foundation, a shadowy organization seeking to destabilize the Earth Sphere Unified Nation and reignite conflict. The Foundation deploys advanced mobile suits and manipulates political factions to achieve its goals.

Heero Yuy, Duo Maxwell, Trowa Barton, Quatre Raberba Winner, and Chang Wufei, the former Gundam pilots, are drawn back into action as the Foundation's plans unfold. Each pilot faces personal challenges while confronting the resurgence of war. Heero and Duo investigate the Foundation's activities, uncovering its ties to Trowa's mysterious past. Quatre struggles with the moral implications of using violence to maintain peace, while Wufei confronts his own ideals of justice. The story explores themes of loyalty, identity, and the cost of peace, as the pilots must decide whether to fight again or protect the fragile stability they helped create.

The manga introduces new characters, including Catherine Bloom, Trowa's sister, who plays a pivotal role in uncovering the Foundation's secrets. The narrative also delves into the psychological toll of war on the pilots, highlighting their growth and struggles in a post-conflict world. The action sequences feature intense mobile suit battles, showcasing the pilots' skills and the advanced technology of the Gundams. The story builds to a climactic confrontation, where the pilots must unite to thwart the Foundation's plans and prevent another catastrophic war. "Blind Target" serves as a bridge between the original series and its sequel, "Endless Waltz," expanding the lore and deepening the characters' arcs.