Misaki Watada is a Japanese voice actress born on March 16 and affiliated with the talent agency Aoni Production. She was born in Iwate Prefecture and raised in Shizuoka Prefecture. Her interest in voice acting began in elementary school after watching videos of actors in the recording studio, which led her to create a clay sculpture titled "Me as a Voice Actress" for a school project. She pursued this passion by enrolling in the Amusement Media Academy, from which she graduated in March 2015. Watada cites fellow voice actress Ikue Ōtani as a major influence, particularly her performance as Stephanie Tanner in the Japanese dub of the American sitcom Full House. This inspiration led to a personal milestone in her career when she voiced the character Pamela in the dub of the sequel series Fuller House in 2017.

Watada's career encompasses a wide range of roles in television animation, original video animations, video games, and dubbing. In television anime, her portrayal of Yaeka Sakuragi, the young daughter of a yakuza boss, in The Yakuza's Guide to Babysitting is a notable leading role. She is also recognized for playing Ume in In the Heart of Kunoichi Tsubaki, Yanai Himeji in Hitori Bocchi no Marumaru Seikatsu, Yuuka Teramoto in If My Favorite Pop Idol Made it to the Budokan, I Would Die, Hikari Yagami in Digimon Adventure:, Klara in Sakura Wars the Animation, Kento Mogami and Mofumofu in Battle Spirits Double Drive, and Hachi in SHIBUYA♡HACHI. She also voiced the character Claire in the 2025 film Eiga Doraemon: Nobita no Esekai Monogatari. In the realm of original net animation, she voiced Corey in The Missing 8.

Watada has demonstrated a recurring collaboration with certain franchises, most notably the Strike The Blood series, where she consistently voiced the character Glenda across multiple installments including Strike The Blood III, Strike The Blood IV, and Strike The Blood FINAL. Another significant recurring role is Delmin in the Show By Rock!! franchise, appearing in Show By Rock!! Mashumairesh!! and Show By Rock!! Stars!!. She has also become a recurring voice in the Sylvanian Families series, taking on the role of Crème in Sylvanian Families: Flare no Happy Diary, Crème Chocolate in Sylvanian Families Freya no Go for Dream! and Sylvanian Families Freya no Piece of Secret. A long-term role is Meisho Doto in the multimedia franchise Uma Musume Pretty Derby, which she has voiced in the television anime, games, and other adaptations since 2018.

Beyond anime, Watada has an extensive body of work in video games. Her game credits include major titles such as Fate/Grand Order as Xu Fu, Digimon Survive as Miu Shinonome, Azur Lane as Miyuki, multiple entries in the God Eater series, and Maglam Lord. She has also been active in foreign-language dubbing for live-action and animated projects, including the role of Rebecca in the Japanese dub of The Chronicles of Rebecca.