Stefania Patruno is an Italian voice actor renowned for her extensive work in dubbing anime and video games. Born in Turin on October 7, 1963, she began her career as an actress in radio and on Italian national television before focusing primarily on voice work. Her voice is characterized as belonging to a middle-aged adult, and she is skilled in delivering performances in Italian, French, and English.

Patruno has lent her voice to a wide array of prominent characters in Japanese animation. One of her most notable roles is that of Tsunade, the Fifth Hokage, in the long-running series Naruto and Naruto: Shippūden. She is also the Italian voice of the stoic cyborg Major Motoko Kusanagi, a role she has performed across multiple iterations of the Ghost in the Shell franchise, including Ghost in the Shell: Stand Alone Complex, its second season 2nd GIG, and the later series Ghost in the Shell: SAC 2045. Her other significant anime credits include the homunculus Lust in both Fullmetal Alchemist and Fullmetal Alchemist: Brotherhood, Lady Une in Mobile Suit Gundam Wing, and Midori Yamabuki in the 1997 remake of What a mess Slump e Arale. She also provided numerous voices for the anthology series Le fiabe di Andersen and voiced Rei "Saint Just" Asaka in Dear Brother.

Beyond animation, Patruno is an extraordinarily prolific voice actor in the video game industry, having voiced characters in many major international franchises for their Italian localizations. Her extensive list of video game credits includes the roles of Dr. Karin Chakwas in the Mass Effect trilogy, Mira Han in StarCraft II, Sonya Blade in Mortal Kombat X, Alex Wesker in Resident Evil: Revelations 2, Aurelia in the Borderlands series, Grace Armstrong in Far Cry 5 and Far Cry New Dawn, and the Revered Mother Prava in Diablo IV. She has also been the voice of the female player character in games like Destiny and Wild Hearts. This body of work across both anime and video games has established Stefania Patruno as a highly respected and recognizable figure in Italian voice acting.