Runo Misaki is a Haos-attribute brawler introduced in the series' first season, achieving sixth global rank. She primarily partners with Haos Tigrerra, evolving into Blade Tigrerra. Her personality blends fierce determination and a hot temper, often reacting strongly to those underestimating her skills due to gender. She shares a close bond with her Bakugan partners, particularly the loyal and powerful Tigrerra. Runo frequently clashes with teammates like Dan Kuso, their relationship evolving into mutual respect marked by unspoken romantic tension. In New Vestroia, her storyline focuses on attempting to follow Dan and Drago. Feeling abandoned, she travels to Moscow with Julie Makimoto to access a dimensional gate. The transport fails, leaving her without a physical body. This incident inadvertently complicates the Resistance by separating members and enables the Vexos to reach Earth. Spectra Phantom later kidnaps her briefly to lure Dan into a confrontation. Though initially set to return to New Vestroia with Dan, she cannot travel, lacking the required gauntlet for the dimensional transporter, and remains on Earth. Her actions this season, including self-blame for setbacks like Mira Fermin losing attribute energy during a joint battle against Mylene and Lync, contribute to her diminishing battlefield presence. Her role significantly diminishes in subsequent seasons. She appears only in flashbacks or photographs during Gundalian Invaders. In Mechtanium Surge, she returns to support the main brawlers by delivering battle suits and briefly partners with Haos Aerogan, who later departs for New Vestroia. She is indirectly involved in major events, such as a timeline where she, Julie, and Mira Fermin are killed by Mechtavius Destroyer—a future later prevented. Across all media, Runo employs multiple Guardian Bakugan beyond Tigrerra: Haos Wolfunoid (later Slicer Wolfunoid) in New Vestroia, Haos Sentanine in Gundalian Invaders, and Haos Malzord and Novax in Mechtanium Surge. Her appearance evolves per season: her initial outfit features a yellow midriff top and white skirt; New Vestroia introduces a yellow shirt with a white-and-pink dress; Mechtanium Surge outfits include khaki shorts and a blue waistcoat. Her background involves helping her parents run a family restaurant, where she initially resents Alice Gehabich for attracting customers, later reconciling this jealousy. A childhood encounter with Dan—forgotten until later—hints at their deeper connection.