"Doctor Chichibuyama Da!" is a comedic manga series that revolves around the eccentric and unorthodox methods of Dr. Chichibuyama, a highly skilled but unconventional physician. The story is set in a small rural hospital where Dr. Chichibuyama works, often clashing with the more traditional medical staff due to his bizarre and sometimes outrageous techniques. Despite his peculiar behavior, Dr. Chichibuyama possesses an uncanny ability to diagnose and treat even the most perplexing medical conditions, often using unconventional methods that defy standard medical practices.

The narrative is episodic, with each chapter typically focusing on a new patient or medical challenge. Dr. Chichibuyama's approach often involves a mix of humor, absurdity, and unexpected ingenuity, leading to both comedic and heartwarming outcomes. His methods, while unorthodox, consistently yield positive results, earning him the grudging respect of his colleagues and the admiration of his patients.

Supporting characters include the hospital staff, who often serve as foils to Dr. Chichibuyama's eccentricities. These characters range from the skeptical chief surgeon to the diligent nurses, each contributing to the dynamic and often chaotic environment of the hospital. The interactions between Dr. Chichibuyama and the staff, as well as the patients, drive much of the series' humor and emotional depth.

The manga balances its comedic elements with moments of genuine medical drama, highlighting the challenges and ethical dilemmas faced by healthcare professionals. Through its unique blend of humor and medical intrigue, "Doctor Chichibuyama Da!" offers a distinctive take on the medical genre, emphasizing the importance of creativity and compassion in the practice of medicine.