"Hitorijime Boyfriend" is a romantic manga series that explores themes of love, relationships, and personal growth through its interconnected characters. The narrative primarily revolves around two central couples, each navigating their own emotional journeys.

The first couple consists of Masahiro Setagawa, a high school student who has long been under the influence of a delinquent group, and Kousuke Ohshiba, a former delinquent turned math teacher. Masahiro, often referred to as "Maa-kun," struggles with his self-worth and the lingering effects of his past associations. Kousuke, known as "Honey-senpai," takes an interest in Masahiro, offering him guidance and protection. Their relationship evolves from a mentor-student dynamic into a deeper romantic connection, as Kousuke helps Masahiro break free from his troubled past and embrace his true self.

The second couple involves Kensuke Ohshiba, Kousuke's younger brother, and Asaya Hasekura, a reserved and studious classmate of Masahiro. Kensuke, a carefree and confident individual, becomes intrigued by Asaya's quiet demeanor and begins to pursue him. Asaya, initially hesitant due to his introverted nature, gradually opens up to Kensuke, leading to a tender and evolving relationship. Their story highlights the challenges of communication and vulnerability in young love.

The series intertwines the lives of these characters, exploring their individual struggles and the ways their relationships shape their growth. Themes of trust, acceptance, and the complexities of human connection are central to the narrative. The manga balances moments of lighthearted humor with emotional depth, creating a multifaceted portrayal of romance and self-discovery. Through its focus on character development and interpersonal dynamics, "Hitorijime Boyfriend" offers a nuanced exploration of love in its various forms.