Anna Nagase is a Japanese voice actress affiliated with the agency 81 Produce. She was born in Tokyo on March 31, 2005. Nagase joined 81 Produce in April 2020 as a junior member, marking the start of her professional career in voice acting. Before focusing on voice work, she had an interest in performing from a young age and was given an opportunity to try voice acting while studying, which she initially found challenging but ultimately motivated her to learn more about the craft.

Nagase's first leading role came in 2022 when she was cast as Ushio Kofune in the suspense anime series Summer Time Rendering. This role was significant not only as her debut as a lead character but also because it required her to perform in the Wakayama dialect, a skill she developed with guidance from fellow cast members. Her performance in Summer Time Rendering was widely recognized and contributed to her receiving the Best New Actor Award at the 17th Seiyu Awards in 2023.

Since her debut, Nagase has built an extensive filmography across a variety of anime series. Her notable roles include Hack in Yurei Deco, Tom in Back Arrow, Tsumugi Himeno in "Ippon" Again!, Mahoro in Bucchigiri?!, Saaya Fujishiro in Tasūketsu, Yōki in 'Tis Time for "Torture," Princess, and Makina in Milky☆Subway: The Galactic Limited Express. In 2024, she voiced the iconic character Harley Quinn in the anime series Suicide Squad Isekai. The following year, in 2025, she was cast as Natsuko Hirose in the original anime ZENSHU.. Her work also extends to video games, where she has voiced characters such as Chixia in Wuthering Waves.

A significant milestone in her career is her casting as the lead character Akane Ōsaki in the 2026 television anime adaptation of Akane-banashi. This role places her at the center of a highly anticipated series and demonstrates her continued growth as a leading voice actress in the industry. Her performance in Akane-banashi is highly anticipated by fans and industry observers alike.