"KamiErabi GOD.app" centers on a group of high school students who are thrust into a deadly competition orchestrated by a mysterious app. The app, known as "GOD.app," selects participants seemingly at random and assigns them the task of eliminating one another to become the "God" of a new world. The narrative explores themes of survival, morality, and the consequences of wielding power.

The protagonist, Rōta Izumida, is an ordinary high school student who becomes entangled in the game after receiving the app on his phone. Alongside him are other participants, each with their own motivations and backstories, including Aoi Hizaki, a determined and resourceful girl, and Kōhei Ashiya, a former delinquent with a hidden sense of justice. The app grants each participant unique abilities, referred to as "GOD powers," which they must use strategically to outwit and defeat their opponents.

As the competition progresses, alliances form and dissolve, and the students are forced to confront the ethical dilemmas of killing others to ensure their own survival. The app's origins and purpose remain shrouded in mystery, with hints suggesting a connection to a larger, more sinister agenda. The story delves into the psychological toll of the game, as characters grapple with guilt, fear, and the loss of their humanity.

The narrative is punctuated by intense battles, strategic confrontations, and moments of introspection as the characters navigate the moral gray areas of their situation. The stakes escalate as the number of participants dwindles, leading to a climactic showdown that challenges the survivors to question the very nature of power and divinity. The series blends action, suspense, and philosophical inquiry, creating a compelling exploration of human nature under extreme circumstances.