"E.Y.E.S. of Mars" is set in a futuristic world where humanity has colonized Mars, creating a society divided by class and power struggles. The narrative centers on the conflict between the ruling elite, known as the Aristocrats, and the oppressed lower-class citizens, referred to as the Commoners. The Aristocrats wield advanced technology and maintain control through a powerful surveillance system, while the Commoners struggle for survival and autonomy in the harsh Martian environment.

The protagonist, a young Commoner named Kakeru, becomes entangled in the conflict after discovering a mysterious artifact known as the "E.Y.E.S." This device grants its user extraordinary abilities, including enhanced physical capabilities and the power to manipulate technology. Kakeru's possession of the E.Y.E.S. draws the attention of both the Aristocrats and a rebel faction fighting for the liberation of the Commoners. As Kakeru learns to harness the artifact's power, he is forced to navigate a complex web of alliances, betrayals, and moral dilemmas.

Key characters include Aria, a skilled rebel leader who becomes Kakeru's mentor and ally, and Lord Zane, the ruthless leader of the Aristocrats, who seeks to claim the E.Y.E.S. for his own ambitions. The story explores themes of resistance, identity, and the consequences of technological advancement, as Kakeru's journey intertwines with the broader struggle for freedom and equality on Mars. The narrative builds toward a climactic confrontation between the forces of oppression and the growing resistance movement, with Kakeru's choices playing a pivotal role in shaping the future of Martian society.