Born in 1981 at Sōgō Hospital, Kagome Higurashi received her name from the "sparkling light" her mother linked to the Shikon Jewel present at her birth. After her father died in a car accident when she was four, her pregnant mother moved the family to the Higurashi Shrine under Grandfather Higurashi's care. On her fifteenth birthday, a centipede demon pulled Kagome into the Bone-Eater's Well, transporting her to Japan's Sengoku period around 1546. There, she found the demon-pinned half-demon Inuyasha and accidentally freed him. During the conflict, the Shikon Jewel, unknown to Kagome, emerged from her body and shattered into fragments by a demonic crow, beginning her quest to retrieve them.
As the reincarnation of the priestess Kikyō, Kagome possessed innate spiritual powers, enabling her to sense Jewel shards and purify demons. Her abilities grew through experience rather than formal training, though she received some guidance from Kaede. Initially vulnerable, she developed archery skills and spiritual techniques like creating barriers and firing purifying arrows. Naraku specifically targeted her because her purification power threatened his existence. A critical test came when the dark priestess Tsubaki corrupted Kagome's Jewel shards, inducing a coma and forcing her to attack Inuyasha. Kagome resisted Tsubaki's control through willpower and Kikyō's intervention, ultimately purifying the shards and breaking the curse.
Kagome's relationship with Inuyasha was complicated by his unresolved connection to Kikyō. Jealousy arising from Inuyasha's protectiveness of Kikyō caused emotional conflict, particularly when he embraced Kikyō after pledging to kill Naraku. This heartbreak led Kagome to temporarily return to her own era. Her romantic feelings solidified after acknowledging her jealousy as love, though Inuyasha's wavering loyalties continued to challenge them. The wolf-demon Kōga's infatuation with Kagome further strained their dynamic, provoking Inuyasha's possessiveness. Despite tensions, Kagome prioritized Inuyasha's well-being, even saving Kikyō for his sake. Kikyō's final death provided closure, allowing Kagome and Inuyasha to reconcile their past.
Kagome balanced her quest in the feudal era with modern life, attending school and aspiring to academic normalcy—goals often dismissed by Inuyasha. Her family supported her travels. After Naraku's defeat, Kagome used the restored Shikon Jewel to wish it out of existence, returning to her era as the connecting well sealed. During a three-year separation, she completed high school while Inuyasha waited at the well. Reuniting through the reopened well, she married Inuyasha and remained in the feudal era as a priestess. They had a daughter, Moroha, who was separated from them as an infant. Years later, Kagome aided her daughter and nieces—Towa and Setsuna—in their battles, employing her matured spiritual powers.