"Honto ni Atta! Reibai-Sensei" is a supernatural comedy anime that revolves around the eccentric and enigmatic Reibai-Sensei, a teacher who specializes in exorcising spirits and solving paranormal mysteries. The series is structured as a collection of episodic stories, each focusing on a different supernatural incident encountered by Reibai-Sensei and his students. The narrative blends humor, horror, and mystery, often incorporating Japanese folklore and urban legends into its plotlines.

Reibai-Sensei, the titular character, is a quirky and unpredictable figure who possesses extensive knowledge of the supernatural. Despite his unorthodox methods and often comical demeanor, he is highly effective in dealing with malevolent spirits and otherworldly phenomena. His classroom serves as a hub for students who find themselves entangled in supernatural occurrences, and he guides them through resolving these issues while imparting lessons about courage, teamwork, and understanding the unknown.

The students, each with distinct personalities, play a significant role in the series. They often act as the audience surrogate, reacting to Reibai-Sensei's bizarre antics and the terrifying situations they face. Their interactions with Reibai-Sensei and the spirits they encounter provide both comedic relief and emotional depth to the narrative. The episodic format allows for a variety of supernatural entities to be explored, ranging from vengeful ghosts and mischievous yokai to cursed objects and haunted locations.

The plot of each episode typically follows a similar structure: a supernatural problem arises, Reibai-Sensei and his students investigate, and the situation is resolved through a combination of wit, knowledge, and sometimes sheer luck. The series balances its darker, more suspenseful moments with lighthearted humor, often poking fun at traditional horror tropes and the absurdity of the situations. While the tone is predominantly comedic, there are instances of genuine tension and emotional weight, particularly when delving into the backstories of the spirits or the personal struggles of the characters.

Overall, "Honto ni Atta! Reibai-Sensei" offers a unique blend of supernatural intrigue and comedic storytelling, anchored by its memorable characters and inventive use of folklore. The episodic nature of the series ensures a diverse range of stories, making it accessible to viewers who enjoy both horror and comedy genres.