"Ore wo Suki na no wa Omae Dake ka yo ~Ore-tachi no Game Set~" is a romantic comedy anime that revolves around the life of Joro, a high school student who finds himself entangled in a complex web of romantic misunderstandings. Joro, who initially presents himself as a kind and selfless individual, is secretly cynical and manipulative, often orchestrating situations to his advantage. His best friend, Sun-chan, is the polar opposite—popular, athletic, and genuinely kind-hearted. Both are admired by their classmate, Cosmos, the student council president, who harbors feelings for Sun-chan.

The story takes a dramatic turn when Joro discovers that Cosmos has written a love letter, which he mistakenly believes is intended for him. However, it is later revealed that the letter is meant for Sun-chan. This misunderstanding sets off a chain of events that complicates the relationships between the three. Joro’s childhood friend, Himawari, who has always been close to him, also becomes involved in the romantic tension. Himawari harbors feelings for Joro but struggles to express them, adding another layer of complexity to the narrative.

As the series progresses, Joro’s manipulative tendencies come to light, causing friction among his friends. The dynamics between the characters shift as secrets are revealed, and the group navigates the challenges of unrequited love, jealousy, and misunderstandings. The story explores themes of self-perception, the masks people wear in social situations, and the consequences of deceit in relationships. The interactions between Joro, Sun-chan, Cosmos, and Himawari drive the plot forward, creating a blend of humor, drama, and emotional moments.

The anime adapts the light novel series by Rakuda, maintaining its focus on the intricate relationships and the comedic yet poignant exploration of teenage romance. The narrative is structured around the characters’ attempts to navigate their feelings while dealing with the fallout of Joro’s schemes. The series balances lighthearted moments with deeper emotional undertones, providing a multifaceted look at the complexities of love and friendship in a high school setting.