"Space Adventure Cobra" is a science fiction anime series set in a futuristic universe where advanced technology and interstellar travel are commonplace. The protagonist, Cobra, is a charismatic and adventurous space pirate with a mysterious past. Cobra possesses a powerful psychic weapon known as the Psychogun, embedded in his left arm, which allows him to unleash devastating energy blasts. His life takes a dramatic turn when he encounters a young woman named Lady Armaroid, an android with a human-like appearance, and becomes entangled in a quest to uncover the secrets of the Pirate Guild, a powerful and enigmatic organization.

The narrative revolves around Cobra’s journey to thwart the Pirate Guild’s plans, which involve manipulating ancient alien artifacts known as the "Crimson Crystal" and the "Golden Armor." These artifacts hold immense power and are sought after by various factions, including the Guild’s leader, Crystal Bowie, a formidable antagonist with his own psychic abilities. Cobra’s mission is further complicated by his encounters with allies and adversaries, including bounty hunters, rogue androids, and alien species, all of whom play pivotal roles in the unfolding conflict.

Throughout the series, Cobra’s past is gradually revealed, including his connection to the Pirate Guild and the reasons behind his transformation into a fugitive. His relationship with Lady Armaroid evolves as they face numerous challenges, blending action, intrigue, and moments of humor. The story is driven by a mix of episodic adventures and an overarching plotline, with Cobra’s quest for freedom and justice serving as the central theme. The series combines elements of space opera, cyberpunk, and classic pulp adventure, creating a dynamic and engaging narrative that explores themes of identity, loyalty, and the pursuit of power in a vast and unpredictable galaxy.