"Nyanbo!" is a short-form anime series that centers around a group of small, cat-like robots known as Nyanbos. These quirky characters are derived from the popular San-X character Danbo, reimagined as feline-inspired robots with cube-shaped bodies. The series is episodic, with each episode presenting self-contained, lighthearted scenarios that highlight the Nyanbos' daily lives and interactions.

The Nyanbos live in a whimsical, everyday world where they engage in simple yet amusing activities. Their adventures often involve playful misunderstandings, creative problem-solving, and humorous attempts to navigate their surroundings. Despite their robotic nature, the Nyanbos exhibit distinctly cat-like behaviors, such as curiosity, mischief, and a penchant for napping. Their interactions with each other and their environment are driven by their unique personalities, which range from energetic and mischievous to shy and contemplative.

The series does not follow a continuous overarching plot but instead focuses on slice-of-life moments that emphasize charm and humor. The Nyanbos' adventures include building makeshift gadgets, exploring their neighborhood, and encountering other quirky characters, both robotic and organic. The tone is consistently light and family-friendly, with a focus on visual gags and gentle humor rather than complex storytelling.

The main characters include the leader-like Nyanbo, who often takes charge of the group; the mischievous and playful Nyanbo, who frequently stirs up trouble; and the shy, timid Nyanbo, who provides a contrast to the others' antics. Their dynamic creates a balance of comedy and heartwarming moments, making the series accessible to viewers of all ages. The simplicity of the narrative and the endearing nature of the characters contribute to the series' appeal as a relaxing and entertaining watch.