"Alice or Alice" is a short-form anime series that centers around the daily lives of twin sisters, Ritsu and Rina, who live together with their older cousin, Arisu. The twins are identical in appearance but have distinct personalities: Ritsu is calm and responsible, while Rina is energetic and mischievous. Arisu, who acts as their caretaker, is a hardworking and nurturing figure, often managing the household and ensuring the twins are well taken care of.

The narrative unfolds in a lighthearted, slice-of-life format, focusing on the playful and often humorous interactions between the three characters. The twins frequently engage in sibling rivalry, competing for Arisu's attention and affection, which leads to comedic situations. Despite their differences, the sisters share a close bond, and their antics are driven by a genuine love for each other and their cousin.

The series explores themes of family, responsibility, and the simple joys of everyday life. Each episode presents self-contained stories, often revolving around mundane activities such as cooking, cleaning, or celebrating holidays, which are infused with a sense of warmth and charm. The twins' contrasting personalities create a dynamic that keeps the narrative engaging, while Arisu's steady presence provides a grounding element to the story.

"Alice or Alice" does not follow a complex or overarching plot but instead emphasizes the small, relatable moments that define the characters' relationships. The series is characterized by its gentle humor, endearing character dynamics, and a focus on the comforting routines of domestic life. It appeals to audiences seeking a light, wholesome viewing experience with a focus on familial love and everyday adventures.