"Me & Roboco" centers around the daily life of a young boy named Bondo Taira, an average elementary school student with a penchant for manga and a somewhat lazy demeanor. His life takes a turn when his mother orders a robotic maid named Roboco from a mysterious company. Roboco, despite her maid designation, is far from ordinary. She possesses immense strength, a quirky personality, and a tendency to cause chaos rather than maintain order. Her arrival disrupts Bondo’s mundane routine, often leading to humorous and unpredictable situations.

The series explores the dynamic between Bondo and Roboco, highlighting their contrasting personalities. Bondo is laid-back and often exasperated by Roboco’s antics, while Roboco is energetic, clumsy, and overly enthusiastic about her duties, even if she frequently misunderstands them. Their interactions form the core of the narrative, with Roboco’s exaggerated attempts to help Bondo often resulting in comedic mishaps. The story also delves into the lives of Bondo’s classmates and friends, including Gachi Gorilla, a muscular and competitive boy, and Motsuo, a quiet and studious character who often finds himself caught up in the chaos Roboco creates.

The episodic structure of the series focuses on slice-of-life scenarios, blending school life, family dynamics, and the absurdity of Roboco’s presence. Themes of friendship, responsibility, and the unpredictability of technology are woven into the narrative, though the primary emphasis remains on humor and lighthearted entertainment. The series balances its comedic tone with moments of warmth, showcasing the growing bond between Bondo and Roboco despite their frequent misunderstandings. Through its quirky characters and absurd situations, "Me & Roboco" offers a playful take on the intersection of everyday life and futuristic technology.