"ESPer Mami: Hoshizora no Dancing Doll" is a two-part OVA that serves as a continuation of the "ESPer Mami" franchise, originally based on Fujiko F. Fujio's manga. The story centers on Mami Sakura, a middle school girl who discovers she possesses psychic abilities, or ESP, which she uses to help others while navigating the challenges of her daily life. The narrative unfolds in a lighthearted yet adventurous tone, blending supernatural elements with slice-of-life moments.

In this installment, Mami encounters a mysterious doll named Lala, who comes to life under the light of a full moon. Lala is revealed to be a creation of an alien scientist who once visited Earth. The doll possesses unique abilities and a connection to the stars, which becomes central to the plot. Mami, along with her friends Kazuo and Toshio, becomes involved in a series of events triggered by Lala's presence. The story explores themes of friendship, responsibility, and the consequences of wielding extraordinary powers.

The plot takes a dramatic turn when Lala's abilities attract the attention of a rival alien faction seeking to exploit her for their own purposes. Mami must use her ESP powers to protect Lala and prevent the aliens from causing harm. The narrative balances action sequences with heartfelt moments, particularly in the interactions between Mami and Lala, as they form a bond that transcends their differences. The story concludes with a resolution that emphasizes the importance of compassion and understanding, as Mami's actions ultimately lead to a peaceful outcome for all involved.

The main characters include Mami Sakura, whose cheerful and determined personality drives the story; Kazuo Takahata, Mami's childhood friend who often provides comic relief; and Toshio Takakura, another friend who occasionally assists Mami in her adventures. Lala, the titular dancing doll, serves as both a catalyst for the plot and a symbol of innocence and wonder. The aliens, though antagonistic, are portrayed with a degree of nuance, reflecting the series' overarching themes of empathy and coexistence. The OVA maintains the charm and whimsy of the original series while introducing new elements that expand the "ESPer Mami" universe.