"Bakuon!!" is a 12-episode anime series that revolves around the daily lives of a group of high school girls who share a passion for motorcycles. The story is set at the Tatenashi Girls' Academy, where the Motorcycle Club serves as the central hub for the characters' adventures and misadventures. The protagonist, Hane Sakura, is a cheerful and somewhat naive first-year student who becomes fascinated with motorcycles after encountering a sleek Honda CB400SF. Her enthusiasm leads her to join the Motorcycle Club, where she meets other members with varying levels of experience and unique personalities.

Rin Suzunoki, the club president, is a stoic and skilled rider who owns a Ducati 916, embodying a cool and composed demeanor. Onsa Amano, a second-year student, is a bubbly and energetic character who rides a Harley-Davidson XL1200S Sportster, often providing comic relief with her over-the-top antics. Hijiri Minowa, another first-year, is a quiet and reserved girl who rides a BMW K1600GT, showcasing her technical knowledge and love for precision. Rounding out the group is Raimu Kawasaki, a third-year student and the club's advisor, who rides a Suzuki Katana and often serves as a mentor figure, despite her eccentric behavior.

The series explores the girls' interactions with motorcycles, from learning to ride and maintain their bikes to participating in club activities and road trips. Each episode highlights different aspects of motorcycle culture, such as the importance of safety gear, the thrill of riding, and the camaraderie among riders. The narrative also delves into the personal growth of the characters as they overcome challenges, both on and off the road. Humor is a consistent element, with exaggerated reactions, slapstick comedy, and playful banter adding a lighthearted tone to the series.

Throughout the series, the girls encounter various motorcycle enthusiasts, including rival riders, mechanics, and even a mysterious biker known as "The Masked Rider," who adds an element of intrigue. The anime balances its comedic moments with educational insights into motorcycle mechanics and history, often featuring real-world models and brands. The blend of humor, character development, and motorcycle-centric content creates a unique narrative that appeals to both fans of slice-of-life anime and motorcycle enthusiasts.