"Seitokai Yakuindomo" is a comedy anime series centered around the daily lives of the student council members at Ousai Academy, a formerly all-girls school that has recently become co-ed. The protagonist, Takatoshi Tsuda, is one of the few male students admitted to the school and is unexpectedly recruited as the vice president of the student council. The council is led by the sharp-tongued and eccentric president, Shino Amakusa, who often engages in risqué humor and innuendo. Other key members include the stoic and deadpan secretary, Aria Shichijou, and the cheerful but naive treasurer, Suzu Hagimura.

The series lacks a central overarching plot, instead focusing on episodic, slice-of-life scenarios that highlight the absurd and humorous interactions between the characters. Much of the comedy stems from the contrast between Takatoshi’s relatively normal demeanor and the council members’ eccentric personalities, particularly their penchant for sexual innuendo and double entendres. Shino frequently teases Takatoshi with suggestive remarks, while Aria’s deadpan delivery and Suzu’s innocent misunderstandings add to the comedic dynamic. The series also features recurring side characters, such as the overenthusiastic class representative, Kotomi Tsuda, and the mischievous Uomi, who often contribute to the chaotic atmosphere.

The humor in "Seitokai Yakuindomo" is heavily reliant on wordplay, situational comedy, and exaggerated character reactions, with a focus on school life and the absurdities of adolescence. The series does not delve deeply into dramatic or romantic developments, instead maintaining a lighthearted tone throughout. Its episodic structure allows for a variety of comedic scenarios, ranging from school festivals and cultural events to mundane council meetings and casual conversations. The interactions between the characters, particularly their banter and misunderstandings, form the core of the series’ appeal, making it a straightforward and accessible comedy with a focus on humor and character dynamics.