"Psychic Force" is a 12-episode anime series based on the fighting video game of the same name. The story is set in a world where individuals with psychic abilities, known as "Psychickers," exist. These Psychickers are often feared and misunderstood by society, leading to their persecution. The narrative centers on the conflict between two factions: the NOA (Neo Organic Alliance), a secretive organization seeking to control Psychickers for their own agenda, and the Psychickers who resist their oppression.

The protagonist, Aoi Kudo, is a young man with latent psychic powers who becomes entangled in the conflict after encountering a mysterious girl named Emilio Mignogna. Emilio is a powerful Psychicker and a key figure in the resistance against NOA. Aoi's journey begins when he is targeted by NOA, forcing him to confront his abilities and the moral complexities of the world he is thrust into. Along the way, he allies with other Psychickers, including the enigmatic Burn Griffiths, a former NOA operative turned rebel, and Keith Evans, a skilled fighter with a personal vendetta against NOA.

The plot explores themes of power, freedom, and the ethical dilemmas surrounding the use of psychic abilities. NOA's leader, Richard Wong, seeks to harness Psychickers' powers to create a new world order, viewing them as tools rather than individuals. This ideology clashes with the resistance's belief in the autonomy and humanity of Psychickers. The series builds toward a climactic confrontation between the resistance and NOA, with Aoi playing a pivotal role in determining the fate of Psychickers worldwide.

Character dynamics are central to the narrative, with relationships evolving amidst the ongoing conflict. Aoi's growth from a reluctant participant to a determined leader forms the emotional core of the story, while supporting characters like Emilio and Burn provide depth and perspective on the broader struggle. The series balances action-packed sequences with moments of introspection, highlighting the personal stakes for each character involved in the fight against NOA.