"Gingitsune" is a supernatural slice-of-life anime centered around the Saeki family, who serve as intermediaries between humans and spirits at a small Shinto shrine. The story primarily focuses on Makoto Saeki, a high school girl who inherits the ability to see and communicate with spirits, a gift passed down through her family. Her companion is Gintarou, a fox spirit messenger of the gods, who has served the Saeki family for generations. Gintarou is wise, often sarcastic, and deeply loyal, acting as both a guide and protector for Makoto.

The narrative unfolds through episodic vignettes, blending everyday life with the mystical. Makoto assists visitors to the shrine, many of whom are troubled by spiritual issues or seek guidance. These encounters often involve resolving conflicts between humans and spirits, uncovering hidden truths, or helping individuals come to terms with their circumstances. The series explores themes of tradition, family, and the coexistence of the mundane and the supernatural.

Supporting characters include Haru, a cheerful and energetic classmate who becomes aware of Makoto's abilities, and Satoru, Makoto's childhood friend who harbors feelings for her. The interactions between these characters add depth to the story, balancing the spiritual elements with relatable human experiences. The shrine itself serves as a central setting, symbolizing the bridge between the human and spirit worlds.

Throughout the series, the relationship between Makoto and Gintarou evolves, highlighting their mutual dependence and the weight of their responsibilities. While Gintarou often provides wisdom and guidance, Makoto's growing confidence and understanding of her role as a mediator become key to resolving many of the challenges they face. The anime maintains a gentle, reflective tone, emphasizing the importance of empathy, communication, and respect for both the seen and unseen worlds.