"By the Grace of the Gods" is a fantasy isekai anime series that centers on Ryoma Takebayashi, a reclusive middle-aged man who dies in his sleep and is reincarnated into a magical world by three deities. The gods grant him a second chance at life, bestowing him with a young body and unique abilities, including the power to communicate with slimes, low-level creatures often dismissed as weak. Ryoma, now a child, is sent to a forest where he lives in solitude, honing his skills and forming bonds with the slimes, which he trains and evolves into more useful forms.

After years of peaceful isolation, Ryoma encounters a group of adventurers who introduce him to the broader world. He decides to leave the forest and integrate into society, settling in the town of Gimul. There, he begins working at a laundromat owned by the Jamil family, using his slimes to innovate and improve the business. His unique abilities and industrious nature quickly earn him recognition, and he forms friendships with townsfolk, including the adventurers Eliaria and Reinhart, who become key figures in his new life.

As Ryoma navigates his new environment, he faces challenges that test his adaptability and resourcefulness. His journey involves balancing his desire for a quiet life with the responsibilities that come with his growing reputation. The series explores themes of personal growth, community, and the value of even the most overlooked creatures, as Ryoma’s bond with slimes becomes a cornerstone of his success. The narrative maintains a lighthearted tone, focusing on slice-of-life moments and gradual character development, while occasionally delving into the broader implications of Ryoma’s abilities and the world’s magical systems. The story progresses through episodic adventures, showcasing Ryoma’s impact on the people and environment around him, as well as his evolving relationships with both humans and slimes.