"Scar on the Praeter" is a supernatural action anime set in a world where humanity coexists with beings known as "Praeters," entities that possess extraordinary powers and are bound by contracts with humans. The story unfolds in a city where these contracts are regulated by a powerful organization called the "Guild," which maintains order between humans and Praeters. However, tensions rise as rogue Praeters and humans begin to exploit these contracts for personal gain, leading to chaos and conflict.

The narrative centers on a young man named Kuga, who becomes entangled in the world of Praeters after a chance encounter with a mysterious girl named Alice. Alice is a Praeter with immense power, and her presence attracts dangerous forces seeking to control or eliminate her. Kuga, despite being an ordinary human, finds himself drawn into the conflict as he forms a contract with Alice, granting him access to her abilities. Together, they navigate a treacherous landscape filled with rival factions, rogue Praeters, and the Guild's enforcers, all while uncovering the truth behind Alice's origins and the deeper mysteries of the Praeters.

Key characters include Kuga, whose determination and growing bond with Alice drive much of the story; Alice, whose enigmatic nature and immense power make her a target; and members of the Guild, such as the stoic enforcer Rindo and the cunning strategist Shiki, who each have their own agendas. The series explores themes of trust, power dynamics, and the consequences of human ambition, as the characters grapple with their roles in a world where the line between ally and enemy is constantly shifting. The plot is driven by a mix of intense action sequences, strategic confrontations, and moments of introspection, as the characters confront their pasts and the choices that define their futures.