"TenPuru" centers on Akemitsu Nakamura, a high school student who, after the death of his parents, is left in the care of his older sister, Yuzuki. Yuzuki, a devout Buddhist nun, runs a small temple where Akemitsu is expected to assist with daily duties. However, Akemitsu struggles with his sister's strict religious lifestyle and her insistence on celibacy, as he harbors a strong desire for romantic and physical relationships. This internal conflict drives much of the narrative, as Akemitsu navigates his responsibilities at the temple while grappling with his personal desires.

The story takes a turn when Yuzuki decides to expand the temple's influence by recruiting new members, leading to the arrival of several eccentric characters. Among them is the cheerful and naive Rinka, a young girl who becomes a novice nun, and the stoic yet enigmatic Koyuki, a skilled martial artist with a mysterious past. These characters bring their own quirks and challenges, creating a dynamic and often comedic environment within the temple. As Akemitsu interacts with them, he finds himself increasingly entangled in their lives, leading to moments of growth, self-reflection, and occasional chaos.

Themes of spirituality, personal growth, and the tension between duty and desire are explored throughout the series. Akemitsu's journey is marked by his attempts to reconcile his worldly aspirations with the expectations placed upon him by his sister and the temple. The interactions between the characters often highlight the contrast between their individual motivations and the collective goal of maintaining the temple's traditions. While the series incorporates humor and lighthearted moments, it also delves into deeper questions about identity, purpose, and the complexities of human relationships. The narrative balances these elements, offering a blend of comedy, drama, and introspection as Akemitsu and the others navigate their shared experiences at the temple.