"Macross 7 the Movie: The Galaxy's Calling Me!" is a condensed retelling of the "Macross 7" television series, reimagined as a feature-length film. The story centers on Nekki Basara, the lead singer of the rock band Fire Bomber, who becomes an unlikely hero in a conflict between humanity and the Protodeviln, an ancient and malevolent alien race. The Protodeviln, led by Geperunichi, seek to drain the life energy of humans and other beings to sustain themselves. Basara, however, believes in the power of music to communicate and resolve conflicts, refusing to engage in traditional warfare.

The narrative unfolds aboard the Macross 7 fleet, a colonization mission traveling through space. When the Protodeviln attack, the military, led by Maximilian Jenius and his wife Mylene, attempts to combat the threat using conventional weapons. However, Basara intervenes, using his music and his transforming Valkyrie fighter, the Sound Force, to reach out to the enemy. His songs, particularly "Planet Dance" and "Try Again," resonate with the Protodeviln, creating a bridge of understanding and challenging their destructive nature.

Key characters include Mylene Jenius, the bassist of Fire Bomber and a skilled Valkyrie pilot, who struggles with her feelings for Basara and her role in the conflict. Gamlin Kizaki, a military officer, serves as a foil to Basara, initially skeptical of his methods but eventually coming to respect his unconventional approach. The Protodeviln, particularly Sivil, a powerful entity who becomes fascinated by Basara's music, play a pivotal role in the story's resolution.

The film culminates in a climactic battle where Basara's music reaches its full potential, disrupting the Protodeviln's plans and forcing them to reconsider their actions. The story emphasizes themes of communication, empathy, and the transformative power of art, as Basara's unwavering belief in music as a universal language ultimately brings about a resolution to the conflict. The film retains the core elements of the "Macross 7" series while streamlining the narrative for a cinematic experience, focusing on the central conflict and Basara's unique approach to peace.