"Uchū Senkan Yamato" to Iu Jidai: Seireki 2202-nen no Sentaku" is a direct sequel to the 2012-2013 reboot series "Space Battleship Yamato 2199," continuing the story of humanity's struggle for survival in the face of interstellar threats. Set in the year 2202, the narrative follows the aftermath of the Yamato's successful mission to retrieve the Cosmo Reverse System from the planet Iscandar, which saved Earth from the radioactive contamination caused by the Gamilas Empire. However, peace proves fleeting as new challenges emerge.

The Earth Federation, emboldened by the Yamato's success, begins expanding its influence across the galaxy, leading to tensions with former allies and enemies alike. The Gatlantis Empire, a militaristic and expansionist force, emerges as a new threat, seeking to conquer Earth and its colonies. The Yamato, now a symbol of hope and resistance, is recommissioned under the command of Susumu Kodai, who must navigate the complexities of war, diplomacy, and personal loss. Alongside Kodai, key characters such as Yuki Mori, Shiro Sanada, and Daisuke Shima return, each grappling with their roles in the escalating conflict.

The story explores themes of sacrifice, the cost of war, and the moral ambiguities of leadership. As the Yamato embarks on a new mission to confront the Gatlantis Empire, the crew faces internal strife, ethical dilemmas, and the resurgence of old enemies. The narrative intertwines personal struggles with large-scale interstellar battles, highlighting the human cost of conflict. The series also delves into the political machinations of the Earth Federation, revealing the darker side of humanity's quest for survival and dominance.

The Gatlantis Empire, led by the enigmatic Zwordar, presents a formidable adversary with advanced technology and a fanatical devotion to their cause. Their arrival forces the Yamato crew to confront not only external threats but also the lingering scars of past wars. The series builds on the legacy of its predecessor while introducing new characters, factions, and technological advancements, creating a rich and expansive narrative that balances action, drama, and introspection. Through its intricate plot and character-driven storytelling, "Uchū Senkan Yamato" to Iu Jidai: Seireki 2202-nen no Sentaku" continues to explore the enduring legacy of the Yamato and its crew in a universe fraught with danger and uncertainty.