"Kenka Banchō Otome: Girl Beats Boys" is a 12-episode anime series based on a visual novel, blending action, comedy, and romance. The story centers on Hinako Nakayama, a high school girl raised in an orphanage, who discovers she has a twin brother, Hikaru Onigashima, the leader of the delinquent group Shishiku Academy's Red Tails. When Hikaru goes missing, Hinako is coerced by her grandfather, the school chairman, to disguise herself as her brother and take his place to maintain order at the school.

Shishiku Academy is a chaotic institution divided into factions, each led by a "banchō" (delinquent leader). Hinako, posing as Hikaru, must navigate this volatile environment while keeping her true identity hidden. Her presence disrupts the power dynamics, as she challenges the banchōs of other factions, including the stoic and disciplined Takayuki Konparu, the flamboyant and unpredictable Ryūji Igarashi, and the enigmatic and aloof Shun Moritsuka. Through her determination and combat skills, Hinako earns their respect and gradually brings stability to the school.

As the series progresses, Hinako's relationships with the banchōs deepen, revealing their individual struggles and motivations. Her interactions with Takayuki, Ryūji, and Shun hint at potential romantic developments, though the focus remains on her mission to restore order and uncover the truth about her brother's disappearance. The narrative balances lighthearted moments with action-packed confrontations, as Hinako's dual identity creates comedic misunderstandings and tense situations.

The series concludes with Hinako successfully uniting the factions and uncovering the mystery behind Hikaru's absence. Her journey highlights themes of identity, loyalty, and the power of perseverance, as she transforms from an outsider to a respected leader. The anime maintains a brisk pace, blending episodic challenges with an overarching plot, and leaves room for further exploration of the characters' relationships and growth.