"Bakemonogatari" centers on Koyomi Araragi, a high school student who survives a vampire attack and retains some supernatural abilities. The series is structured as a series of interconnected arcs, each focusing on Araragi's interactions with various girls afflicted by supernatural phenomena, known as "oddities." These oddities often manifest as metaphors for personal struggles or emotional conflicts.

The first arc introduces Hitagi Senjougahara, a classmate who suffers from a condition where she weighs almost nothing due to an oddity. Araragi helps her confront the entity responsible, leading to a deeper connection between the two. Their evolving relationship becomes a recurring thread throughout the series.

Subsequent arcs explore other characters and their encounters with oddities. Mayoi Hachikuji, a lost spirit searching for her mother, represents themes of regret and unresolved grief. Suruga Kanbaru, a talented athlete, struggles with a demonic arm that grants immense power but corrupts her desires. Nadeko Sengoku, a shy girl, becomes entangled with a snake spirit that amplifies her insecurities. Tsubasa Hanekawa, Araragi's classmate and confidante, deals with a split personality caused by a supernatural cat.

Each arc blends supernatural elements with psychological and emotional depth, often resolving the oddity through introspection and personal growth. The narrative is driven by sharp, dialogue-heavy exchanges, with Araragi serving as both a protagonist and a guide for the afflicted characters. The series balances humor, mystery, and philosophical undertones, creating a unique storytelling style.

The overarching plot gradually reveals more about Araragi's past as a vampire and his relationship with Meme Oshino, a mysterious man who helps him and others deal with oddities. While the arcs are largely self-contained, they contribute to a broader exploration of human nature, relationships, and the consequences of supernatural interference in the mundane world. The series concludes with a sense of continuity, leaving room for further exploration in subsequent installments of the Monogatari franchise.