"Lupin the 3rd: Bye Bye, Lady Liberty" is a feature-length anime special that centers on the exploits of the master thief Arsène Lupin III and his team. The story begins with Lupin targeting the Statue of Liberty, aiming to steal a hidden treasure rumored to be concealed within its structure. The treasure, a priceless artifact known as the "Liberty Statue," is said to possess immense historical and monetary value. Lupin's plan involves infiltrating the iconic monument during a high-profile event, leveraging his signature wit, gadgets, and disguises to outmaneuver security.

The narrative introduces Inspector Zenigata, Lupin's relentless pursuer from Interpol, who is determined to thwart the heist. Zenigata's efforts are complicated by the involvement of a mysterious organization with its own agenda regarding the treasure. This group, led by a cunning and resourceful antagonist, employs advanced technology and a network of operatives to challenge Lupin at every turn. The dynamic between Lupin and Zenigata remains a central element, blending rivalry with moments of reluctant cooperation as their paths intersect.

Lupin's team, including the sharpshooter Jigen, the swordsman Goemon, and the enigmatic Fujiko Mine, play pivotal roles in the heist. Each character contributes their unique skills, with Jigen providing firepower, Goemon offering precision, and Fujiko navigating her own motives, often oscillating between ally and rival. The interplay among the team members adds depth to the narrative, showcasing their camaraderie and occasional conflicts.

The plot unfolds with a series of intricate schemes, daring escapes, and high-stakes confrontations. Lupin's plan evolves as he uncovers layers of deception surrounding the treasure, revealing connections to historical events and powerful figures. The story maintains a brisk pace, balancing action, humor, and suspense, while exploring themes of ambition, loyalty, and the allure of the unattainable.

The climax takes place within the Statue of Liberty, where Lupin and his adversaries engage in a final showdown. The resolution ties together the various threads of the narrative, leaving the fate of the treasure and the characters' relationships open to interpretation. The special concludes with Lupin and his team departing, ready for their next adventure, while Zenigata vows to continue his pursuit, ensuring the cycle of cat-and-mouse continues.