"Sekkō Boys" is a 12-episode anime series that blends comedy, slice-of-life, and idol culture with a unique twist. The story centers around Miki Ishimoto, a young woman who reluctantly becomes the manager of an idol group called Sekkō Boys. The twist lies in the group's composition: the members are not human but four ancient Greek and Roman marble busts—Mars, Hermes, Medici, and Saint Giorgio. Despite their inanimate appearance, the busts possess distinct personalities and the ability to speak, sing, and interact with the world.

Miki, initially skeptical and overwhelmed by the absurdity of managing statues, gradually becomes invested in their success. The series explores her efforts to navigate the challenges of promoting the Sekkō Boys in the competitive idol industry, where their unconventional nature often leads to comedic misunderstandings and obstacles. The busts themselves are characterized by their quirks: Mars is brash and confident, Hermes is laid-back and carefree, Medici is refined and aloof, and Saint Giorgio is stoic and mysterious. Their interactions with Miki and the world around them drive much of the humor and heart of the series.

The plot unfolds through episodic adventures, with each episode focusing on a specific challenge or event, such as recording a single, participating in a variety show, or dealing with rival idol groups. The series balances its comedic elements with moments of sincerity, particularly in Miki's growing dedication to her role and the busts' occasional reflections on their existence and purpose. While the premise is inherently absurd, the show uses its unique concept to explore themes of identity, perseverance, and the often unpredictable nature of the entertainment industry.

The supporting cast includes Miki's friend and fellow manager, Kanji Tsukino, who provides additional comedic relief, as well as various industry professionals and rival idols who interact with the Sekkō Boys. The series maintains a lighthearted tone throughout, with occasional nods to art history and classical culture, given the busts' origins. Overall, "Sekkō Boys" offers a humorous and unconventional take on the idol genre, blending its bizarre premise with relatable character dynamics and a steady stream of comedic situations.