"Asura Cryin'" is a supernatural mecha anime that intertwines elements of science fiction, fantasy, and mystery. The story centers on Tomoharu Natsume, a high school student who lives alone in his family's old house after the death of his parents. His life takes a dramatic turn when he discovers that his childhood friend, Misao Minakami, who died years ago, has returned as a ghost and now resides with him. Misao's presence is tied to a mysterious artifact known as the "Asura Machina," a powerful mechanical entity that only Tomoharu can activate.

Tomoharu's ordinary life unravels further when he becomes entangled in a conflict involving various factions vying for control of the Asura Machina. These factions include the enigmatic Kurogane Agency, which seeks to harness the artifact's power, and the "Asura Cryin'," individuals who possess the ability to summon and control these machines. As Tomoharu learns more about his connection to the Asura Machina, he discovers that his existence is intertwined with a parallel world where the rules of reality are distorted. This alternate dimension, known as the "Demon World," is linked to the Asura Machina and plays a crucial role in the unfolding events.

Throughout the series, Tomoharu is joined by a diverse cast of characters, each with their own motivations and ties to the Asura Machina. These include Kanade Takatsuki, a classmate with a mysterious past and her own connection to the artifact, and Shuri Kurosaki, a member of the Kurogane Agency who initially appears as an antagonist but later becomes an ally. The narrative explores themes of identity, sacrifice, and the consequences of wielding immense power, as Tomoharu grapples with his role in the conflict and the moral dilemmas it presents.

The plot is driven by a series of escalating confrontations between the factions, with Tomoharu and his allies striving to prevent the Asura Machina from falling into the wrong hands. The story delves into the origins of the Asura Machina, its connection to the Demon World, and the true nature of Tomoharu's abilities. As the stakes grow higher, the lines between friend and foe blur, and Tomoharu must confront the possibility that his actions could have far-reaching consequences for both worlds.

The series balances action-packed mecha battles with moments of introspection and character development, creating a narrative that is both engaging and thought-provoking. The interplay between the real world and the Demon World adds a layer of complexity to the story, as characters navigate the shifting boundaries between the two realms. By the conclusion, the series ties together its various plot threads, offering a resolution that addresses the central conflicts while leaving room for interpretation regarding the characters' futures.