"Plastic Little" is a two-episode OVA series set in a futuristic world where humanity has colonized a gas giant planet named Yietta. The story centers on Tita, a young girl who captains the spaceship Cha Cha Maru, a vessel primarily used for capturing exotic sea creatures in the planet's dense atmosphere. Tita and her crew, including the skilled navigator Elysse and the mechanic Barton, navigate the treacherous skies of Yietta, balancing their adventurous lifestyle with the challenges of survival in a harsh environment.

The plot begins when Tita rescues a mysterious girl named Elysse from a group of armed pursuers. Elysse is revealed to be a fugitive, hunted by a powerful military organization due to her connection to a secretive research project. As Tita and her crew take Elysse under their protection, they become entangled in a dangerous conspiracy involving advanced biotechnology and political intrigue. The narrative explores themes of trust, loyalty, and the consequences of scientific experimentation, as the crew of the Cha Cha Maru must outwit their pursuers and uncover the truth behind Elysse's plight.

The series features a mix of action, adventure, and science fiction elements, with a focus on the dynamics between the characters. Tita is portrayed as a determined and resourceful leader, while Elysse's vulnerability and hidden strength add depth to her character. The supporting cast, including the pragmatic Barton and the enigmatic Elysse, contribute to the story's tension and emotional stakes. The OVA's concise runtime ensures a fast-paced narrative, with a balance of character-driven moments and high-stakes action sequences. The setting of Yietta, with its unique blend of oceanic and atmospheric environments, provides a visually distinct backdrop for the story's events.