"Sabagebu!" centers on Momoka Sonokawa, a high school girl who reluctantly joins the Survival Game Club at her new school. The club, led by the assertive and eccentric Miou Ootori, engages in mock battles using airsoft guns. Despite her initial hesitation, Momoka quickly adapts to the club's chaotic and competitive environment, often employing cunning and ruthless tactics to outwit her opponents. The series blends action, comedy, and satire, with each episode featuring exaggerated survival game scenarios that parody military and survival tropes.

The club members include Miou, who is both skilled and manipulative, often bending the rules to her advantage; Kayo Goutokuji, a stoic and disciplined markswoman; Maya Kyoudou, a cheerful and energetic member with a knack for improvisation; and Urara Kasugano, a shy and reserved girl who harbors a dark, violent side. The group frequently faces off against rival clubs, school authorities, and even fantastical adversaries, with the narrative emphasizing humor and over-the-top action over realism.

Momoka's internal monologues and fourth-wall-breaking commentary add a meta-comedic layer to the series, as she frequently critiques the absurdity of the situations she finds herself in. The plot is episodic, with each episode presenting a new challenge or scenario for the Survival Game Club, often culminating in elaborate and unpredictable battles. The series maintains a lighthearted tone, using its premise to explore themes of friendship, competition, and the absurdity of high school club culture, all while delivering fast-paced, comedic action.