"Generator Gawl" is a 12-episode anime series that blends science fiction, action, and mystery. The story is set in a near-future world where genetic engineering has advanced significantly, leading to the creation of genetically modified creatures known as Generators. These beings possess extraordinary abilities and are often used as weapons or tools by various factions. The narrative centers on three young men—Gawl, Ryo, and Koji—who travel back in time from a dystopian future to prevent the catastrophic consequences of unchecked genetic experimentation.

The trio arrives in the year 2007, posing as students at a prestigious academy where Professor Nekasa, a key figure in genetic research, is conducting experiments that will eventually lead to the creation of Generators. Gawl, the protagonist, is a Generator himself, designed to combat other Generators. Ryo and Koji, his companions, provide technical and strategic support. Their mission is to sabotage Nekasa's work and alter the timeline to avert the future they come from.

As the story progresses, Gawl and his team face numerous challenges, including encounters with other Generators sent to eliminate them. These battles reveal the ethical dilemmas surrounding genetic engineering and the moral ambiguity of their mission. The series explores themes of identity, free will, and the consequences of scientific advancement, as Gawl struggles with his own nature as a weapon and his desire to protect humanity.

Key characters include Masami, a fellow student who becomes romantically involved with Gawl, and Natsume, a mysterious girl with her own connection to the Generator project. The interactions between these characters add emotional depth to the narrative, highlighting the personal stakes involved in their mission. The series builds toward a climactic confrontation with Nekasa and the forces seeking to exploit Generator technology, culminating in a resolution that balances action with philosophical reflection on the implications of their actions.