"Comic Party Revolution" is a 12-episode anime series that centers on Kazuki Sendou, a high school student who becomes involved in the world of doujinshi, or self-published manga. Initially uninterested in the hobby, Kazuki is introduced to the doujinshi scene by his friend Taishi Kuhonbutsu, an avid creator and participant in comic conventions. Taishi convinces Kazuki to attend a doujinshi event, where he encounters a vibrant community of creators and fans. Intrigued by the passion and creativity of the participants, Kazuki decides to try his hand at creating his own doujinshi, despite having no prior experience.

The series explores Kazuki's journey as he navigates the challenges of creating and selling doujinshi, balancing his school life with his newfound passion. Along the way, he meets a variety of characters who influence his growth, including Mizuki Takase, a talented artist who becomes his rival and eventual collaborator, and Yuu Inagawa, a cheerful and supportive friend who helps him with his projects. Other key characters include Eimi Ohba, a professional manga artist who offers guidance, and Chisa Tsukamoto, a shy but dedicated doujinshi creator.

As Kazuki delves deeper into the doujinshi world, he faces numerous obstacles, such as tight deadlines, creative blocks, and the competitive nature of the industry. The series highlights the camaraderie and rivalries within the community, as well as the personal struggles of the characters as they pursue their artistic ambitions. Kazuki's relationships with the other characters evolve throughout the series, with moments of collaboration, conflict, and mutual support.

The narrative also touches on the broader themes of artistic expression, perseverance, and the importance of community. Kazuki's journey is not just about creating doujinshi but also about discovering his own identity and learning to balance his aspirations with the realities of life. The series provides a detailed look at the doujinshi culture, from the creative process to the logistics of participating in conventions, offering an informative and engaging portrayal of this unique subculture.