"Subete ga F ni Naru," also known as "The Perfect Insider," is an 11-episode anime series adapted from the mystery novel of the same name by Hiroshi Mori. The story revolves around a locked-room murder mystery set on a remote island, blending elements of psychological thriller and intellectual drama.

The narrative centers on Shiki Magata, a reclusive and enigmatic genius programmer who has lived in isolation for 15 years following the murder of her parents, a crime for which she was the prime suspect but never convicted. Shiki resides in a high-tech research facility on an isolated island, where she continues her work on artificial intelligence. The facility is visited by Sohei Saikawa, a university professor specializing in architecture and design, and his brilliant student Moe Nishinosono. Moe, who harbors a deep admiration for Shiki, convinces Saikawa to accompany her to the island to meet the elusive programmer.

Upon their arrival, the duo discovers that Shiki has been murdered under mysterious circumstances. The crime scene is a locked room, with no apparent way for the killer to enter or exit. As the investigation unfolds, Saikawa and Moe are drawn into a complex web of clues, philosophical musings, and psychological intrigue. The story delves into themes of human consciousness, the nature of identity, and the boundaries between reality and illusion, often referencing Shiki's work on AI and her philosophical beliefs.

The investigation reveals that Shiki's death is connected to her past, including the unresolved murder of her parents and her controversial theories on human existence. As Saikawa and Moe piece together the puzzle, they uncover shocking truths about Shiki's life, her relationships, and the events leading up to her death. The series maintains a tense and cerebral atmosphere, with each episode building on the mystery and challenging the characters—and the audience—to question their assumptions.

The main characters include Sohei Saikawa, whose analytical mind and calm demeanor make him a natural investigator, and Moe Nishinosono, whose emotional investment in Shiki's story adds a personal dimension to the mystery. Shiki Magata, though deceased for much of the series, remains a central figure through flashbacks and her lingering influence on the narrative. The interplay between these characters drives the story forward, as they navigate the labyrinthine mystery and confront the philosophical questions it raises.

The series concludes with a resolution that ties together the various threads of the mystery, offering explanations for the locked-room scenario and the motivations behind the crimes. However, it leaves room for interpretation, particularly regarding the philosophical and existential themes explored throughout the story. "Subete ga F ni Naru" is a thought-provoking and meticulously crafted mystery that appeals to fans of intellectual storytelling and intricate plotlines.