"Ange Vierge" is set in a world where multiple dimensions have collided, creating a phenomenon known as the "Hollow Rain." This event merges five parallel worlds into one, each with its own unique characteristics and inhabitants. The collision also brings forth mysterious entities called "Exceed," which threaten the stability of the newly unified world. To combat this threat, the "Progress" organization is established, training young girls known as "Progress Girls" to harness their abilities and protect the world from the Exceed.

The story centers on Amane, a shy and reserved girl who becomes a Progress Girl after being transported to the White Garden, one of the training facilities for these warriors. Amane possesses a unique ability called "Linker," which allows her to amplify the powers of others. Alongside her are other Progress Girls, including Saya, a confident and skilled fighter; Code Omega 77 "Hime," a mysterious girl with immense power; and Code Omega 88 "Almaria," a cheerful and energetic character. Together, they form a team to face the Exceed and uncover the secrets behind the Hollow Rain.

As the series progresses, the girls undergo rigorous training and engage in battles against increasingly powerful Exceed. The narrative explores their personal growth, relationships, and the challenges they face as they strive to protect their world. Themes of friendship, teamwork, and self-discovery are woven into the plot, as the characters confront their fears and insecurities while learning to rely on one another.

The story also delves into the origins of the Hollow Rain and the true nature of the Exceed, revealing deeper layers of intrigue and conflict. The Progress Girls must navigate not only external threats but also internal struggles within their organization, as hidden agendas and rivalries come to light. The series balances action-packed battles with moments of introspection, creating a dynamic narrative that keeps viewers engaged.

"Ange Vierge" features a diverse cast of characters, each with distinct personalities and abilities, contributing to the richness of the story. The interplay between the characters drives the plot forward, as they work together to overcome obstacles and uncover the truth behind the dimensional collision. The series concludes with a resolution to the immediate conflict, while leaving room for further exploration of the world and its mysteries.