"Seven of Seven" is a 26-episode anime series that blends elements of comedy, romance, and science fiction. The story centers on Nana Suzuki, an ordinary middle school girl who dreams of becoming a great inventor like her grandfather. Her life takes an unexpected turn when she accidentally creates a device that splits her into seven identical clones, each with distinct personalities and traits. These clones represent different aspects of Nana's character, ranging from shy and studious to bold and mischievous.

The clones, all named Nana, must navigate their shared existence while keeping their true nature a secret from the outside world. Each clone develops unique relationships with the people around them, including Nana's childhood friend, Tetsuya, who becomes increasingly confused by the sudden changes in her behavior. The series explores the challenges of maintaining individuality while sharing a single identity, as well as the comedic and emotional consequences of their predicament.

As the story progresses, the Nanas face various situations that test their unity and adaptability. From school events to personal dilemmas, each clone contributes their strengths and weaknesses to overcome obstacles. The series also delves into Nana's aspirations as an inventor, with her clones often assisting in her experiments, which sometimes lead to further chaos. The dynamic between the clones and their interactions with supporting characters drive much of the narrative, creating a mix of lighthearted humor and heartfelt moments.

The plot occasionally introduces external conflicts, such as rival inventors or misunderstandings that threaten to expose the clones' secret. However, the focus remains on the Nanas' growth as individuals and their collective journey to find balance and purpose. The series concludes with a resolution that ties together the themes of identity, friendship, and self-discovery, offering a satisfying end to the Nanas' unique adventure.