"SSSS.Gridman" is a 12-episode anime series that reimagines the 1993 tokusatsu series "Gridman the Hyper Agent." The story is set in the fictional Japanese city of Tsutsujidai, where high school student Yuta Hibiki suffers from amnesia. One day, he discovers an old computer in his friend Rikka Takarada's junk shop, which houses the consciousness of Gridman, a mysterious being who claims to be a Hyper Agent. Gridman reveals that Yuta is his chosen partner and that they must work together to protect the city from kaiju, monstrous creatures that threaten its inhabitants.

As Yuta begins to regain fragments of his memory, he learns that the kaiju are manifestations of human emotions, created by a malevolent entity known as Alexis Kerib. Alexis manipulates events from a hidden dimension, using a human named Akane Shinjo as his pawn. Akane, a classmate of Yuta and Rikka, is unaware of the full extent of her role in the chaos. She creates kaiju unconsciously, driven by her frustrations and desires, which Alexis exploits to destabilize the city.

Yuta, with the help of Gridman and his allies—Rikka, Utsumi Shou, and the virtual support team known as the Neon Genesis Junior High Students—engages in battles against the kaiju. Each encounter reveals more about the true nature of Tsutsujidai, which is revealed to be a fabricated reality constructed by Alexis. The city and its inhabitants are part of a simulated world, with Akane serving as its unwitting architect. As Yuta and Gridman grow stronger, they uncover the layers of deception and confront the existential threat posed by Alexis.

The series explores themes of identity, reality, and the consequences of escapism. Akane's character arc is central to the narrative, as her struggles with loneliness and dissatisfaction mirror the broader conflict between creation and destruction. The climax sees Yuta and Gridman confronting Alexis in a final battle to save both Akane and the city. The resolution emphasizes the importance of facing reality and the power of human connection, leaving the characters to rebuild their lives in a world that is no longer bound by illusion.