"Last Exile ~Fam, The Silver Wing~" is a 2011 anime series set in the same universe as the original "Last Exile" but with a new cast of characters and a focus on a different region of the world. The story takes place on the divided continent of Prester, where the powerful Turan Kingdom and the Ades Federation are locked in a conflict over territory and resources. The Turan Kingdom, ruled by the young Princess Liliana, relies on advanced technology and airships to maintain its independence, while the Ades Federation seeks to expand its empire through military conquest.

Fam Fan Fan, a skilled and adventurous sky pirate, and her close friend Giselle Collette Vingt, pilot a small vanship and live by scavenging and performing daring aerial maneuvers. Their lives change when they witness the Ades Federation's brutal attack on the Turan capital, Anatoray. During the invasion, they rescue Princess Liliana and her younger sister, Millia, who are fleeing the destruction of their homeland. The sisters become central figures in the resistance against Ades, with Fam and Giselle joining their cause.

As the conflict escalates, Fam and her allies uncover the deeper motivations behind Ades's aggression, including the mysterious "Exile," a legendary artifact said to grant immense power to those who control it. The search for the Exile becomes a driving force for both sides, with Fam and her friends navigating political intrigue, shifting alliances, and personal sacrifices. The series explores themes of loyalty, identity, and the cost of war, as the characters grapple with their roles in the unfolding struggle.

The narrative is driven by a mix of aerial combat, political maneuvering, and character development. Fam's optimism and determination contrast with the more reserved and strategic Liliana, while Giselle provides a grounded perspective. The series also introduces a range of supporting characters, including members of the Turan military, Ades officers, and other sky pirates, each contributing to the complex web of relationships and conflicts. The story builds toward a climactic confrontation that ties together the fates of the characters and the future of Prester.