"Cat's Eye" is a crime-adventure anime series centered around the Kisugi sisters—Rui, Hitomi, and Ai—who operate a café by day and moonlight as master thieves. Their primary objective is to recover a collection of artworks stolen by their father, a renowned painter who mysteriously disappeared years earlier. Each piece of art contains clues to his whereabouts, and the sisters use their skills in disguise, combat, and strategy to steal these works from museums, private collections, and galleries. Their heists are meticulously planned, often leaving behind their signature calling card: a drawing of a cat's eye.

The series introduces Toshio Utsumi, a detective determined to capture the elusive thieves. Unbeknownst to him, his fiancée, Hitomi, is one of the sisters he is pursuing. This creates a complex dynamic as Hitomi struggles to balance her loyalty to her family with her feelings for Toshio. The tension between the sisters' dual lives and Toshio's relentless investigations forms a central narrative thread, blending action, mystery, and emotional conflict.

The Kisugi sisters' heists are often elaborate, involving clever disguises, high-tech gadgets, and intricate plans to outwit security systems and law enforcement. Their targets are carefully chosen, each tied to their father's collection, and the series frequently delves into the backstory of the artworks and their significance. As the story progresses, the sisters uncover more about their father's disappearance, revealing a larger conspiracy that ties their missions to a broader criminal network.

The series balances episodic heist plots with an overarching mystery, maintaining a steady pace of action and intrigue. The characters are defined by their distinct personalities: Rui, the eldest, is the strategic leader; Hitomi, the middle sister, is empathetic and torn between her dual roles; and Ai, the youngest, is energetic and tech-savvy. Their camaraderie and shared mission drive the narrative, while their interactions with Toshio and other recurring characters add depth to the story.

"Cat's Eye" combines elements of crime, adventure, and romance, with a focus on the sisters' quest to reunite their family. The series explores themes of loyalty, identity, and the moral ambiguity of their actions, as they navigate the fine line between right and wrong in their pursuit of justice for their father. The blend of action-packed sequences, emotional stakes, and a compelling mystery makes it a distinctive entry in the crime-adventure genre.