"Chobits" is a science fiction romance anime set in a world where personal computers have evolved into humanoid forms known as Persocoms. These Persocoms resemble humans and are capable of complex interactions, serving as companions, assistants, or even romantic partners. The story centers on Hideki Motosuwa, a young man from a rural area who moves to Tokyo to attend a preparatory school. Struggling financially, Hideki dreams of owning a Persocom but cannot afford one. One evening, he discovers an abandoned Persocom in the trash, resembling a beautiful young woman. After activating her, he names her Chii, as she can only say the word "Chii" initially.

Chii exhibits childlike behavior and lacks basic knowledge, prompting Hideki to teach her about the world while caring for her. As their bond deepens, Hideki becomes increasingly curious about Chii's origins and her unusual abilities, which set her apart from other Persocoms. Chii possesses advanced capabilities, such as bypassing security systems and displaying emotions beyond standard programming. These traits hint at her being a unique model, possibly part of the rumored "Chobits" series, a mysterious line of Persocoms with unparalleled intelligence and autonomy.

The narrative explores themes of artificial intelligence, human relationships, and the ethical implications of creating sentient machines. Hideki's interactions with Chii raise questions about the nature of love and whether it can exist between a human and a machine. Supporting characters, such as Hideki's landlady, Ms. Hibiya, and his classmate, Shinbo, provide additional perspectives on Persocoms and their role in society. Ms. Hibiya, who owns a Persocom named Sumomo, offers guidance to Hideki, while Shinbo, a Persocom programmer, becomes involved in uncovering Chii's true identity.

As the story progresses, Chii begins to recover fragments of her memory, revealing cryptic messages and images that suggest a deeper purpose. Flashbacks and dreams hint at a connection between Chii and a man named Freya, who may hold the key to her existence. The narrative builds toward a resolution that addresses Chii's origins, her relationship with Hideki, and the broader implications of Persocom technology. The series balances lighthearted moments with philosophical undertones, creating a thought-provoking exploration of humanity's relationship with technology.