"Street Fighter IV: The Ties That Bind" is an anime OVA that serves as a prequel to the events of the video game "Street Fighter IV." The narrative centers around the global martial arts tournament organized by the mysterious organization S.I.N., led by Seth, a powerful fighter seeking to harness the energy of the world's strongest warriors. The story primarily follows Ryu, a wandering martial artist, as he confronts his inner struggle with the Satsui no Hado, a dark and destructive force within him. Ryu's journey intertwines with other iconic fighters, including Ken Masters, Chun-Li, and Guile, who are drawn into the conflict due to their own motivations and connections to S.I.N.

Chun-Li, an Interpol officer, investigates S.I.N.'s activities, uncovering their plans to create advanced bioweapons using the DNA of elite fighters. Guile, a former military operative, joins her in the pursuit of justice, driven by personal vendettas. Meanwhile, Ken Masters, Ryu's longtime friend, becomes entangled in the chaos when his family is threatened by S.I.N.'s machinations. The narrative explores themes of rivalry, loyalty, and the ethical dilemmas surrounding power and technology.

As the story progresses, the fighters confront Seth and his elite enforcers, including Crimson Viper, a skilled operative with her own agenda. The battles highlight the unique fighting styles and philosophies of each character, culminating in a climactic showdown that sets the stage for the events of "Street Fighter IV." The OVA effectively bridges the gap between the game's lore and its characters, providing insight into their motivations and relationships while maintaining a focus on action and martial arts. The plot emphasizes the interconnectedness of the fighters' lives, illustrating how their individual paths converge in the face of a shared threat.