"Glitter Force Doki Doki" is a magical girl anime series that centers around a group of young girls who transform into superheroes to protect their world from evil forces. The story is set in the peaceful kingdom of Splendorius, which is threatened by the malevolent King Mercenare and his minions, who seek to steal the "Miraculous Prism" and spread despair across the universe. The Miraculous Prism is a powerful artifact that embodies hope and positivity, and its destruction would plunge the world into chaos.

The protagonist, Mana Aida, is a cheerful and kind-hearted middle school student who becomes the leader of the Glitter Force. After encountering a fairy named Sharuru, Mana is chosen to wield the power of the Miraculous Prism and transform into Glitter Heart, the leader of the Glitter Force. Alongside her, four other girls join the team: Rikka Hishikawa, a diligent and intelligent student who becomes Glitter Diamond; Alice Yotsuba, a reserved and wealthy girl who transforms into Glitter Rosetta; Makoto Kenzaki, a tomboyish and athletic girl who becomes Glitter Sword; and Regina, a mysterious girl with a connection to King Mercenare, who later joins the team as Glitter Ace.

Each member of the Glitter Force possesses unique abilities and weapons, which they use to combat the "Jikochuu," monsters created by King Mercenare's minions to spread negativity and despair. The Jikochuu are born from the negative emotions of humans, and the Glitter Force must not only defeat these monsters but also help the affected individuals overcome their inner struggles. Throughout the series, the team faces various challenges, including personal conflicts, moral dilemmas, and the growing threat of King Mercenare's plans.

As the story progresses, the Glitter Force uncovers the truth about Regina's origins and her ties to King Mercenare. Regina, initially an antagonist, struggles with her identity and loyalty, eventually choosing to join the Glitter Force to fight for hope and justice. The series explores themes of friendship, courage, and the power of positivity, as the girls work together to protect their world and restore balance.

The narrative builds toward a climactic battle against King Mercenare, who seeks to destroy the Miraculous Prism and plunge the universe into eternal despair. The Glitter Force must harness the full power of their friendship and the Miraculous Prism to defeat him and save Splendorius. The series concludes with the girls reaffirming their commitment to protecting their world and spreading hope, leaving the door open for future adventures.